431 research outputs found

    PERCEPÇÕES E REAÇÕES DE PROFESSORES DIANTE DAS POLÍTICAS EDUCACIONAIS: UM ESTUDO COM PROFESSORES DE EDUCAÇÃO FÍSICA

    Get PDF
    RESUMOEste estudo busca compreender como os professores de Educação Física atuantes na Rede Estadual de Ensino do Rio Grande do Sul percebem e reagem às políticas educacionais que lhes são demandadas pelos gestores estaduais nas ultimas três gestões do governo estadual do Rio Grande do Sul. Neste sentido foi realizada uma pesquisa qualitativa na perspectiva da etnografia. Como obtenção de informações foram realizadas: observações participantes do cotidiano dos professores de Educação Física, registrada nos diários de campo; entrevistas semiestruturadas com cinco professores de Educação Física e análise de documentos. Através da análise foi possível construir unidades de significado que agrupadas resultaram em três categorias analíticas: a indiferença, a resistência e as marcas. Compreendemos que o professorado de Educação Física participante deste estudo atua em dado momento da sua prática pedagógica com indiferença e resistências às políticas educacionais formuladas pelos gestores. É possível pensarmos que a resistência dos professores é potencializada quando eles são convidados a preterir elementos da sua história de vida que estão imbricados na sua prática pedagógica.Palavras-chave: Ensino Médio. Trabalho docente. Políticas Educacionais. Prática Pedagógica. ABSTRACTThis study aims to understand how Physical Education teachers from Rio Grande do Sul public state schools follow and react to educational policies demanded by the local and state authorities from the last three state government management of Rio Grande do Sul. In this context, a research focused on ethnography was conducted. To obtain information, there were performed observations in the daily routine of Physical Education teachers, recorded in the field journal; semi-structured interviews with five Physical Education teachers and data analyses. Because of the analyses, it was possible to build meaning units, which organized, result in three analytical categories: the indifference, the resistance, and the marks. The results suggest that the Physical Education teachers, who participated the study, act in their teaching practice indifferently and resistant to educational policies formulated by the state managers. It suggests that the resistance of the teachers is reinforced when they are led to ignore elements from their own life experience which are interwoven with their teaching practices.Keywords: High School. Teaching. Educational policies. Teaching practices

    A singular finite element for Stokes flow: The stick–slip problem

    Full text link
    Abrupt changes in boundary conditions in viscous flow problems give rise to stress singularities. Ordinary finite element methods account effectively for the global solution but perform poorly near the singularity. In this paper we develop singular finite elements, similar in principle to the crack tip elements used in fracture mechanics, to improve the solution accuracy in the vicinity of the singular point and to speed up the rate of convergence. These special elements surround the singular point, and the corresponding field shape functions embody the form of the singularity. Because the pressure is singular, there is no pressure node at the singular point. The method performs well when applied to the stick–slip problem and gives more accurate results than those from refined ordinary finite element meshes.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/50199/1/1650091105_ftp.pd

    Vaccine associated benign headache and cutaneous hemorrhage after ChAdOx1 nCoV-19 vaccine: A cohort study

    Get PDF
    Objectives Fatal complications have occurred after vaccination with ChAdOx1 nCoV-19, a vaccine against Covid-19. Vaccine-induced immune thrombotic thrombocytopenia (VITT) with severe outcome is characterized by venous thrombosis, predominantly in cerebral veins, thrombocytopenia and anti-PF4/polyanion antibodies. Prolonged headaches and cutaneous hemorrhages, frequently observed after the ChAdOx1 nCoV-19 vaccine, have therefore caused anxiety among vaccinees. We investigated whether these symptoms represent a mild form of VITT, with a potential for aggravation, e.g. in case of a second vaccination dose, or a different entity of vaccine complications Materials and methods We included previously healthy individuals who had a combination of headache and spontaneous severe cutaneous hemorrhages emerging after the 1st dose of the ChAdOx1 nCoV-19 vaccine. Twelve individuals were found to meet the inclusion criteria, and a phone interview, cerebral MRI, assessment of platelet counts, anti PF4/polyanion antibodies and other laboratory tests were performed. Results None of the symptomatic vaccinees had cerebral vein thrombosis, hemorrhage or other pathology on MRI. Platelet counts were within normal range and no anti-PF4/polyanion platelet activating antibodies were found. Moreover, vasculitis markers, platelet activation markers and thrombin generation were normal. Furthermore, almost all symptoms resolved, and none had recurrence of symptoms after further vaccination with mRNA vaccines against Covid-19. Conclusions The combination of headaches and subcutaneous hemorrhage did not represent VITT and no other specific coagulation disorder or intracranial pathology was found. However, symptoms initially mimicking VITT demand vigilance and low threshold for a clinical evaluation combined with platelet counts and D–dimer

    Immune complexes, innate immunity, and NETosis in ChAdOx1 vaccine-induced thrombocytopenia

    Get PDF
    Aims - We recently reported five cases of vaccine-induced immune thrombotic thrombocytopenia (VITT) 7–10 days after receiving the first dose of the ChAdOx1 nCoV-19 adenoviral vector vaccine against corona virus disease 2019 (COVID-19). We aimed to investigate the pathogenic immunological responses operating in these patients. Methods and results - We assessed circulating inflammatory markers by immune assays and immune cell phenotyping by flow cytometry analyses and performed immunoprecipitation with anti-platelet factor (PF)4 antibody in plasma samples followed by mass spectrometry from all five patients. A thrombus was retrieved from the sinus sagittal superior of one patient and analysed by immunohistochemistry and flow cytometry. Precipitated immune complexes revealed multiple innate immune pathway triggers for platelet and leucocyte activation. Plasma contained increased levels of innate immune response cytokines and markers of systemic inflammation, extensive degranulation of neutrophils, and tissue and endothelial damage. Blood analyses showed activation of neutrophils and increased levels of circulating H3Cit, dsDNA, and myeloperoxidase–DNA complex. The thrombus had extensive infiltration of neutrophils, formation of neutrophil extracellular traps (NETs), and IgG deposits. Conclusions - The results show that anti-PF4/polyanion IgG-mediated thrombus formation in VITT patients is accompanied by a massive innate immune activation and particularly the fulminant activation of neutrophils including NETosis. These results provide novel data on the immune response in this rare adenoviral vector-induced VITT

    Thoracic outlet syndrome in a patient with absent scalenus anterior muscle

    Get PDF
    This case report describes the rare anomaly of an absent right anterior scalene muscle presenting with the symptoms and signs of the thoracic outlet syndrome. The thoracic outlet syndrome in our patient can be attributed to the absence of the right anterior scalene muscle, which resulted in the brachial plexus being in proximity to the subclavian vein and artery in a narrowed and abnormal interscalene space. In addition, the absence of the anterior scalene muscle resulted in the neurovascular structures being compressed onto the first rib in the costoclavicular space. The most likely cause of the presentation is, however, the possibility of the presence of aberrant muscle slips, which would cause compression of the structures in the anterior (venous) and posterior (neurological) sections of the thoracic outlet.http://journals.lww.com/cjsportsmed/pages/default.aspxhb201

    Driving pressure during general anesthesia for open abdominal surgery (DESIGNATION) : study protocol of a randomized clinical trial

    Get PDF
    Background Intraoperative driving pressure (Delta P) is associated with development of postoperative pulmonary complications (PPC). When tidal volume (V-T) is kept constant, Delta P may change according to positive end-expiratory pressure (PEEP)-induced changes in lung aeration. Delta P may decrease if PEEP leads to a recruitment of collapsed lung tissue but will increase if PEEP mainly causes pulmonary overdistension. This study tests the hypothesis that individualized high PEEP, when compared to fixed low PEEP, protects against PPC in patients undergoing open abdominal surgery. Methods The "Driving prESsure durIng GeNeral AnesThesIa for Open abdomiNal surgery trial" (DESIGNATION) is an international, multicenter, two-group, double-blind randomized clinical superiority trial. A total of 1468 patients will be randomly assigned to one of the two intraoperative ventilation strategies. Investigators screen patients aged >= 18 years and with a body mass index <= 40 kg/m(2), scheduled for open abdominal surgery and at risk for PPC. Patients either receive an intraoperative ventilation strategy with individualized high PEEP with recruitment maneuvers (RM) ("individualized high PEEP") or one in which PEEP of 5 cm H2O without RM is used ("low PEEP"). In the "individualized high PEEP" group, PEEP is set at the level at which Delta P is lowest. In both groups of the trial, V-T is kept at 8 mL/kg predicted body weight. The primary endpoint is the occurrence of PPC, recorded as a collapsed composite of adverse pulmonary events. Discussion DESIGNATION will be the first randomized clinical trial that is adequately powered to compare the effects of individualized high PEEP with RM versus fixed low PEEP without RM on the occurrence of PPC after open abdominal surgery. The results of DESIGNATION will support anesthesiologists in their decisions regarding PEEP settings during open abdominal surgery

    Nesting Biology and Fungiculture of the Fungus-Growing Ant, Mycetagroicus cerradensis: New Light on the Origin of Higher Attine Agriculture

    Get PDF
    The genus Mycetagroicus is perhaps the least known of all fungus-growing ant genera, having been first described in 2001 from museum specimens. A recent molecular phylogenetic analysis of the fungus-growing ants demonstrated that Mycetagroicus is the sister to all higher attine ants (Trachymyrmex, Sericomyrmex, Acromyrmex, Pseudoatta, and Atta), making it of extreme importance for understanding the transition between lower and higher attine agriculture. Four nests of Mycetagroicus cerradensis near Uberlândia, Minas Gerais, Brazil were excavated, and fungus chambers for one were located at a depth of 3.5 meters. Based on its lack of gongylidia (hyphal-tip swellings typical of higher attine cultivars), and a phylogenetic analysis of the ITS rDNA gene region, M. cerradensis cultivates a lower attine fungus in Clade 2 of lower attine (G3) fungi. This finding refines a previous estimate for the origin of higher attine agriculture, an event that can now be dated at approximately 21–25 mya in the ancestor of extant species of Trachymyrmex and Sericomyrmex

    Monitoring extracellular pH, oxygen, and dopamine during reward delivery in the striatum of primates

    Get PDF
    Dopamine projections that extend from the ventral tegmental area to the striatum have been implicated in the biological basis for behaviors associated with reward and addiction. Until recently, it has been difficult to evaluate the complex balance of energy utilization and neural activity in the striatum. Many techniques such as electrophysiology, functional magnetic resonance imaging (fMRI), and fast-scan cyclic voltammetry have been employed to monitor these neurochemical and neurophysiological changes. In this brain region, physiological responses to cues and rewards cause local, transient pH changes. Oxygen and pH are coupled in the brain through a complex system of blood flow and metabolism as a result of transient neural activity. Indeed, this balance is at the heart of imaging studies such as fMRI. To this end, we measured pH and O2 changes with fast-scan cyclic voltammetry in the striatum as indices of changes in metabolism and blood flow in vivo in three Macaca mulatta monkeys during reward-based behaviors. Specifically, the animals were presented with Pavlovian conditioned cues that predicted different probabilities of liquid reward. They also received free reward without predictive cues. The primary detected change consisted of pH shifts in the striatal extracellular environment following the reward predicting cues or the free reward. We observed three types of cue responses that consisted of purely basic pH shifts, basic pH shifts followed by acidic pH shifts, and purely acidic pH shifts. These responses increased with reward probability, but were not significantly different from each other. The pH changes were accompanied by increases in extracellular O2. The changes in pH and extracellular O2 are consistent with current theories of metabolism and blood flow. However, they were of sufficient magnitude that they masked dopamine changes in the majority of cases. The findings suggest a role of these chemical responses in neuronal reward processing
    corecore